In vitro antiproliferative/cytotoxic activity on cancer cell lines of a cardanol and a cardol enriched from Thai Apis mellifera propolis

Table 3 The yield and character of the five CHE fractions obtained after quick column chromatography

Fraction	Weight (mg)	Yield (% of CHE/total propolis)	Character	Antiproliferative/ cytotoxic activity^a	TLC plates^b
I	80	0.36%/0.09%	Clear wax	--	3
II	20	0.09%/0.02%	Clear yellow oil	--	3
III	320	1.42%/0.36%	Yellow oil	3 cell lines	1
IV	270	1.2%/0.30%	Yellow powder	2 cell lines	3
V	4,300	19.1%/4.78%	Dark brown oil	all 5 cell lines	2

^aNumber of the five human cancer cell lines in which a significant antiproliferative/cytotoxic activity was induced by the extract after a 72 h exposure, as determined by the MTT assay
^bThe minimum number of distinct compounds in the fraction as determined by evaluation of the different TLC plates

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