Genes investigated | ND240 | HFD60 | HFD120 | HFD240 | HFDMET |
---|
IL-6
| −1.17±0.67 | −1.38±0.41c
| −1.11±0.20d
| −3.27±0.92b
| −1.35±0.03c
|
CRP
| −2.10±0.60 | 0.10±0.78a
| −4.00±0.21b
| −3.40±0.87b
| −2.30±0.12c
|
MCP-1
| −1.63±0.45 | 1.09±0.14b
| −2.33±0.24c
| −1.33±0.69d
| −1.20±1.10d
|
SAA-2
| −1.55±0.66 | −5.53±0.47b
| −5.39±0.54b
| −5.67±0.95b
| −3.82±0.77c
|
NF-κB
| −1.11±0.37 | −2.30±0.29b
| −2.90±0.92c
| −2.30±0.30b
| −2.45±1.13b
|
TNF-α
| −3.46±0.09 | 1.16±0.21b
| −4.50±0.43c
| −4.11±0.37c
| −1.79±1.06d
|
- Results are expressed as –fold variation over the appropriate control groups; ND240 indicate fold increase over ND, normal diet control group and HFD60, HFD120, HFD240 and HFDMET indicate fold increase over HFD, high-fat diet control group. Fold variations less than one were expressed as negative numbers (e.g., a –fold variation of 0.50 is expressed as −2.00). Values expressed are means ± S.D of triplicate measurements. Statistical significance was calculated based on the mean ΔCT values by DMRT for only mice fed with high-fat diet with or without GE. For same gene with different treatment groups, means in the different rows with different alphabets (a-d) were significantly different (p<0.05).