Paeoniflorin regulates macrophage activation in dimethylnitrosamine-induced liver fibrosis in rats

Table 2 Effects of PF on serum parameters in DMN-induced rat liver fibrosis ( $\bar{x} \pm s$ )

Group(number)	ALT(U/L)	AST(U/L)	ALP(U/L)	TP (g/L)	Alb (g/L)	TBil(μmol/L)
Normal (10)	25.14±2.86^△▴	79.00±5.83^△▴	226.71±24.68^△▴	57.60±1.95^△▴	29.15±1.13^△ ▴▴	2.40±0.08^⋆
2-week DMN (3)	90.33±3.21▴	182.67±11.93▴	395.00±53.11▴	48.53±4.55▴	26.33±1.82▴▴	3.30±0.17^⋆
DMN-water (5)	256.80±144.26^△	549.40±260.71^△	667.60±41.20^△	30.82±5.02^△	18.94±0.89^△△	79.00±21.13^☆
DMN-PF (7)	127.43±20.19▴	234.86±42.56▴	394.00±34.03▴	46.98±3.73▴	25.37±1.96^▴▴	31.97±12.34^⋆
DMN-GdCl₃(6)	230.20±43.27	425.60±79.67	610.80±51.16▴	34.14±3.06	20.68±3.05	68.96±15.07

^Δ p<0.05 versus 2-week DMN rats; ▴p<0.05 versus DMN-water rats. Bonferron’s multiple comparison test were used for group comparisons in ALT, AST, ALP, TP, and Alb.
^☆ p<0.05 versus 2-week DMN rats; ^⋆ p<0.05 versus DMN-water rats. Kruskal-Willam test were used for group comparisons in TBil

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