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Table 2 Bax/Bcl-2 ratio of mRNA expression

From: Modulation of apoptosis in human hepatocellular carcinoma (HepG2 cells) by a standardized herbal decoction of Nigella sativa seeds, Hemidesmus indicus roots and Smilax glabra rhizomes with anti- hepatocarcinogenic effects

Dose of the decotion

Bax/Bcl-2

 

12 h

24 h

48 h

Control

0.484

0.489

0.468

75 μg/ml

0.603

0.663

0.827

150 μg/ml

0.758

0.920

1.020

300 μg/ml

1.074

1.220

1.410

600 μg/ml

1.660

1.886

2.180

1200 μg/ml

2.254

2.792

3.857

  1. Bax/Bcl-2 ratio was up regulated in a time and dose dependent manner
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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