Figure 2

Alteration of escape latency and swimming distance during an acquisition test using the water maze. Four trials per day for 4 consecutive days were conducted and the escape latency (A and A') and swimming distance (B and B') were measured. Representative images (C) showing the swimming path of mice during the tests. Left: drug non treated- hPS2 transgenic mice and right: drug treated-hPS2 transgenic mice. Data are presented as mean ± SEM, and comparisons between the two groups were evaluated by the unpaired t-test. *P < 0.05 compared to the drug treated-hPS2 transgenic mice.