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Table 6 Analysis on effect of drug intervention against fibrogenesis induced by bile duct-ligation in rats (n = 7, x ¯ ± s )

From: A comparative study on the hepatoprotective action of bear bile and coptidis rhizoma aqueous extract on experimental liver fibrosis in rats

Group Sample (n) Fibrosis phase Fibrotic area within 1.5 mm2(mm2)
   0 1 2 3  
Normal 7 7 0 0 0 0
Shamed 7 7 0 0 0 0
Model 7 0 2 1 4 0.88 ± 0.46
Silymarin 7 0 3 2 2 0.62 ± 0.21*
Berberine 7 0 4 2 1 0.38 ± 0.25**
CRAE 7 0 4 2 1 0.55 ± 0.21*
Bear Bile 7 0 5 1 1 0.32 ± 0.19**
TUDCA 7 0 3 1 3 0.61 ± 0.32
  1. p < 0.05 when compared with normal group; p < 0.01 when compared with normal group; *p < 0.05 when compared with model group; **p < 0.01 when compared with model group.