Skip to main content

Table 4 Effect of test materials and propanolol (reference control) on mean arterial blood pressure of rats

From: Anticancer activities against cholangiocarcinoma, toxicity and pharmacological activities of Thai medicinal plants in animal models

Group

Dose

(mg/kg bw.)

Mean arterial pressure (mmHg)

  

Before induction of hypertension

After induction of hypertension

After treatment of hypertension

Normal

-

107 ± 3.1

110 ± 3.4

109 ± 2.7

Untreated control

-

108 ± 3.4

143 ± 2.7

151 ± 3.0

Propanolol-treated

10

110 ± 3.2

145 ± 3.1

116 ± 2.5*

CUR

1000

106 ± 0.4

145 ± 0.3

138 ± 0.5

 

3000

104 ± 0.3

146 ± 0.4

137 ± 0.4

 

5000

107 ± 0.3

148 ± 0.3

135 ± 0.4

ZO

1000

105 ± 0.3

144 ± 0.4

135 ± 0.5

 

3000

107 ± 0.4

147 ± 0.5

137 ± 0.3

 

5000

106 ± 0.3

148 ± 0.4

119 ± 0.3*

AL

1000

105 ± 0.3

148 ± 0.5

118 ± 0.4*

 

3000

107 ± 0.4

144 ± 0.4

120 ± 0.4*

 

5000

106 ± 0.3

148 ± 0.4

122 ± 0.3*

PC

100

103 ± 0.3

147 ± 0.3

134 ± 0.5

 

500

105 ± 0.4

149 ± 0.4

124 ± 0.4*

 

1000

105 ± 0.4

147 ± 0.4

125 ± 0.4*

PPF

1000

104 ± 0.3

145 ± 0.4

134 ± 0.3

 

2000

108 ± 0.4

146 ± 0.5

134 ± 0.4

 

4000

104 ± 0.4

143 ± 0.5

134 ± 0.5

  1. Data are presented as mean ± SEM values
  2. *Statistically significant difference with baseline by paired t-test:
  3. sBP and dBP of ZO-treated group at high dose level (p < 0.001)
  4. sBP and dBP of AL-treated group at all dose levels (p < 0.001)
  5. sBP and dBP of PC-treated group at medium and high dose levels (p < 0.001)
  6. sBP and dBP of propanolol-treated group (p < 0.001)
Back to article page

BMC Complementary Medicine and Therapies

ISSN: 2662-7671

Contact us