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Table 5 Effects of rutin on body weight, kidney weight and relative kidney weight of rat

From: Protective effects of rutin against potassium bromate induced nephrotoxicity in rats

Treatment

Percent increase in body weight (g) after

Absolute kidney weight (g)

Relative kidney weight (% to bw)

Ist week

2nd week

3rd week

4rth week

Control

6.3±0.6++

13.4±1.3++

21.3±2.3++

28.2±3.4++

4.0±0.08++

0.040±0.00072++

Saline (0.5 ml/kg bw; 0.9% NaCl)

6.6±0.5++

13.8±2.1++

22.4±2.6++

27.6±3.2++

4.0±0.08++

0.040±0.00072++

KBrO3 (20 mg/kg bw)

3.4±0.3**

7.6±1.5**

10.2±1.6**

14.4±2.6**

4.9±0.60**

0.049±0.00125**

KBrO3+Rutin (50 mg/kg bw)

4.4±0.3*++

10.4±1.2*++

15.3±1.4*++

19.6±2.4++

4.50±0.12++

0.045±0.00079++

KBrO3+Rutin (70 mg/kg bw)

4.9±0.4++

12.6±1.4++

19.6±1.5++

23.4±3.2++

4.23±0.14++

0.042±0.0014++

Rutin alone (70 mg/kg bw)

6.2±0.4++

14.8±1.3++

22.7±1.6++

27.8±2.4++

4.12±0.06++

0.041±0.00049++

  1. Mean ±SEM (n=6 number).
  2. *, ** indicate significance from the control group at P<0.05 and P<0.01 probability level, respectively.
  3. ++ indicate significance from the KBrO3 group at P<0.01 probability level.