From: Protective effects of rutin against potassium bromate induced nephrotoxicity in rats
Treatment | Percent increase in body weight (g) after | Absolute kidney weight (g) | Relative kidney weight (% to bw) | |||
---|---|---|---|---|---|---|
Ist week | 2nd week | 3rd week | 4rth week | |||
Control | 6.3±0.6++ | 13.4±1.3++ | 21.3±2.3++ | 28.2±3.4++ | 4.0±0.08++ | 0.040±0.00072++ |
Saline (0.5 ml/kg bw; 0.9% NaCl) | 6.6±0.5++ | 13.8±2.1++ | 22.4±2.6++ | 27.6±3.2++ | 4.0±0.08++ | 0.040±0.00072++ |
KBrO3 (20 mg/kg bw) | 3.4±0.3** | 7.6±1.5** | 10.2±1.6** | 14.4±2.6** | 4.9±0.60** | 0.049±0.00125** |
KBrO3+Rutin (50 mg/kg bw) | 4.4±0.3*++ | 10.4±1.2*++ | 15.3±1.4*++ | 19.6±2.4++ | 4.50±0.12++ | 0.045±0.00079++ |
KBrO3+Rutin (70 mg/kg bw) | 4.9±0.4++ | 12.6±1.4++ | 19.6±1.5++ | 23.4±3.2++ | 4.23±0.14++ | 0.042±0.0014++ |
Rutin alone (70 mg/kg bw) | 6.2±0.4++ | 14.8±1.3++ | 22.7±1.6++ | 27.8±2.4++ | 4.12±0.06++ | 0.041±0.00049++ |