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Table 4 Comparison of the frequency and duration of acute exacerbation

From: Effects of comprehensive therapy based on traditional Chinese medicine patterns in stable chronic obstructive pulmonary disease: a four-center, open-label, randomized, controlled study

Variable

Full analysis set

Per-protocol analysis set

 

Trial n=175

Control n=175

t/Z

P

Trial n=155

Control n=151

t/Z

P

Frequency (times)

Month 0

3.26 ± 2.27

2.94 ± 2.05

1.378

0.169

3.32 ± 2.31

2.95 ± 1.91

1.523

0.129

Month 6

1.02 ± 1.51

1.71 ± 2.14

−3.484

0.001

0.97 ± 1.26

1.48 ± 1.81

−2.888

0.004

Month 18

0.49 ± 0.77

1.09 ± 1.15

−5.689

0.000

0.54 ± 0.75

1.01 ± 0.98

−4.798

0.000

Average frequency

1.01 ± 1.26

1.95 ± 1.88

−5.509

0.000

1.02 ± 1.08

1.76 ± 1.47

−4.963

0.000

Frequency (constituent ratio)

Have exacerbation

101

136

18.5857

0.000

92

121

15.6084

0.000

None exacerbation

76

37

63

30

Duration(days)

Average duration

4.20 ± 5.20

6.22 ± 5.15

−3.653

0.000

4.39 ± 5.24

6.37 ± 5.19

−3.323

0.001