Figure 4

Effect of MMC, (g/kg, p.o) on stereotypies and climbing time induced by methamphetamine in mice. (a) Each point represents the mean ± SEM from the stereotypy scores obtained from six animals. (b) The cumulative stereotypy scores were measured during 30 to 60 min after administration of methamphetamine. (c) Total time spent on the wall of the cage. ### p < 0.001, ## p < 0.01 compared with that of the saline group; *p< 0.05, ** p < 0.01, ***p <0.001 compared with that of the methamphetamine (METH, mg/kg, i.p) group. Haloperidol (2 mg/kg, i.p) showed 100% inhibition on methamphetamine-induced stereotypies in mice (data not shown). n.s- not significant.