Figure 7From: Cucurbitacin B inhibits human breast cancer cell proliferation through disruption of microtubule polymerization and nucleophosmin/B23 translocation Morphological changes by cucurbitacin B treatment of breast cancer cells . MCF-7 and MDA-MB-231 cells were treated with 2.5 μM cucurbitacin B for 24 hr, and the cells were visualized under phase-contrast microscopy to investigate the morphological alteration. Shrinkage and rounding of the cell shape were observed in both cell types.Back to article page