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Table 5 Effect of Rutin on assessment of oxidative stress

From: CCl4-induced hepatotoxicity: protective effect of rutin on p53, CYP2E1 and the antioxidative status in rat

Treatment

CAT (U/min)

SOD (U/mg protein)

GST nM /min/mg protein

GSH-Px nM/min/mg protein

GSR nM /min/mg protein

GSH (μM /g tissue)

TBARS (nM /min/mg protein)

Control

4.81±0.10++

22.71±1.18++

192.12±2.49++

84.12±5.19++

127.23±10.52++

1.23±0.02++

28.33±1.12++

3 ml/kg CCl4

2.91±0.06**

11.91±0.38**

104.23±2.14**

46.12±3.62**

62.33±9.28**

0.60±.01**

52.17±2.61**

50 mg/kg Rutin+CCl4

4.60±0.16++

19.52±0.47++

175.21±2.19++

70.23±4.31++

101.13±9.14++

1.17±0.04++

31.17±1.74++

70 mg/kg Rutin+CCl4

5.03±0.09++

21.41±0.62++

183.32±3.09++

80.12±6.82++

121.12±12.24++

1.18±0.01++

27.14±1.22++

  1. Mean ±SE (n=6 number).
  2. ** indicate significance from the control group at P< 0.01 probability level.
  3. ++ indicate significance from the CCl4 group at P< 0.01 probability level.
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BMC Complementary Medicine and Therapies

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