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Table 4 Effect of Rutin on Indices of hepatotoxicity

From: CCl4-induced hepatotoxicity: protective effect of rutin on p53, CYP2E1 and the antioxidative status in rat

Treatment

ALT (U/L)

AST (U/L)

ALP (U/L)

γ-GT (nM/min /mg protein)

Control

52.11±2.12++

76.32±2.74++

198.10±3.93++

105.25±2.22++

3 ml/kg CCl4

111.01±3.42**

234.10±4.27**

470.13±6.49**

154.03±3.02**

50 mg/kg Rutin+CCl4

58.01±2.68++

102.13±4.99++

227.05±3.89++

111.03±3.04++

70 mg/kg Rutin+CCl4

56.12±2.05++

98.61±2.75++

209.06±3.68++

107.23±2.01++

  1. Mean ±SE (n=6 number).
  2. ** indicate significance from the control group at P< 0.01 probability level.
  3. ++ indicate significance from the CCl4 group at P< 0.01 probability level.