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Table 5 Lipoxygenase activity of crude extracts and fractions of 6 plants from the Mascarene Islands

From: Antioxidant, antiglycation and cytotoxicity evaluation of selected medicinal plants of the Mascarene Islands

Concentrations (μg/mL)

Lipoxygenase inhibition

 

Crude water extract

Crude methanol extract

Dichloromethane

Ethylacetate

n-butanol

Water fraction

10

82.46 ± 10.09*

79.75 ± 10.07*

77.88 ± 6.37*

53.71 ± 4.17*

27.46 ± 1.77*

32.80 ± 1.31*

 

{97.06 ± 11.67*}

{98.32 ± 7.64*}

{81.21 ± 5.24*}

{63.94 ± 3.13*}

{74.98 ± 2.23*}

{67.81 ± 4.47*}

 

[53.69 ± 2.36*]

[38.88 ± 1.09*]

[52.54 ± 0.95*]

[53.31 ± 1.26*]

[17.87 ± 1.01*]

[48.64 ± 2.07*]

 

(13.59 ± 1.01)

(23.03 ± 0.95*)

(41.13 ± 1.68*)

(30.96 ± 1.33*)

(13.35 ± 0.67)

(13.11 ± 0.67)

 

∫10.39 ± 0.96∫

∫9.39 ± 1.01∫

∫9.45 ± 0.34∫

∫11.69 ± 0.66∫

∫12.39 ± 1.03∫

∫ 9.68 ± 0.91∫

 

1.23 ± 0.02

5.62 ± 0.68

0.96 ± 0.02

2.36 ± 0.02

14.96 ± 0.66*

2.85 ± 0.51

5

69.37 ± 9.37*

62.69 ± 6.11*

58.37 ± 3.64*

28.67 ± 3.09*

11.09 ± 0.67

19.67 ± 0.99

 

{70.16 ± 5.55* }

{83.67 ± 4.36*}

{68.69 ± 2.01*}

{42.67 ± 3.15*}

{56.04 ± 2.16*}

{46.39 ± 3.37*}

 

[37.11 ± 1.39*]

[18.39 ± 2.67*]

[29.67 ± 0.36*]

[36.56 ± 0.76*]

[9.36 ± 0.67]

[32.05 ± 1.16*]

 

(7.51 ± 0.77)

(16.37 ± 0.88*)

(28.34 ± 1.09*)

(14.36 ± 1.45*)

(7.57 ± 0.84)

(8.34 ± 0.34)

 

∫9.67 ± 0.82∫

∫7.64 ± 0.36∫

∫6.37 ± 0.22∫

∫ 6.37 ± 0.98∫

∫7.72 ± 0.23∫

∫5.37 ± 0.62∫

 

0.96 ± 0.03

2.37 ± 0.11

0.57 ± 0.01

1.09 ± 0.03

7.09 ± 0.35

1.06 ± 0.02

2.5

56.09 ± 7.67*

50.37 ± 3.07*

32.67 ± 1.06*

20.37 ± 2.01*

7.19 ± 0.65

9.37 ± 0.67

 

{53.37 ± 4.31*}

{62.37 ± 3.16*}

{50.37 ± 2.67*}

{37.65 ± 1.11*}

{39.67 ± 1.97*}

{35.67 ± 2.01*}

 

[26.09 ± 1.03*]

[10.09 ± 1.37]

[13.06 ± 0.26]

[27.39 ± 1.03*]

[5.36 ± 0.58]

[24.31 ± 1.09*]

 

(3.36 ± 0.17)

(8.67 ± 0.36)

(12.04 ± 1.11)

(8.34 ± 0.67)

(5.01 ± 0.11)

(5.06 ± 0.25)

 

∫6.37 ± 0.66∫

∫4.09 ± 0.46∫

∫4.36 ± 0.07∫

∫4.09 ± 0.54 ∫

∫4.46 ± 0.33∫

∫3.64 ± 0.36∫

 

0.67 ± 0.02

1.06 ± 0.02

0.36 ± 0.02

0.67 ± 0.02

4.53 ± 0.54

0.97 ± 0.06

1.25

32.37 ± 2.07*

29.67 ± 2.01*

28.03 ± 0.45*

11.09 ± 0.37

2.37 ± 0.53

4.09 ± 0.36

 

{42.37 ± 2.01*}

{48.69 ± 2.16*}

{32.69 ± 1.97*}

{13.39 ± 0.12}

{26.67 ± 1.37*}

{29.67 ± 1.36*}

 

[10.09 ± 0.96]

[6.37 ± 0.65]

[7.63 ± 0.11]

[11.03 ± 0.15]

[3.34 ± 0.27]

[9.03 ± 0.37]

 

(1.55 ± 0.01)

(5.34 ± 0.11)

(9.37 ± 0.15)

(5.34 ± 0.60)

(2.09 ± 0.03)

(2.04 ± 0.11)

 

∫2.39 ± 0.09∫

∫1.96 ± 0.02∫

∫2.34 ± 0.03∫

∫2.39 ± 0.23∫

∫1.07 ± 0.07∫

∫1.37 ± 0.01∫

 

0.29 ± 0.01

0.64 ± 0.01

0.24 ± 0.01

0.47 ± 0.01

2.07 ± 0.16

0.17 ± 0.01

  1. Note. Values are means ± SD of three independent experiments. AM {FF}[OT] (MC) ∫EM∫ PS. *Values significantly different (p < 0.05) from the control in each group.