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Table 2 Minimum Inhibitory concentrations of costunolide and eremanthin isolated from Costus speciosus against tested fungi using microdilution technique (μg/ml)

From: Antimicrobial activity of sesquiterpene lactones isolated from traditional medicinal plant, Costus speciosus (Koen ex.Retz.) Sm

Tested organisms Costunolide Eremanthin Fluconazole Ketoconazole
Trichophyton mentagrophytes 62.5 125 25 < 12.5
Trichophyton simii 31.25 62.5 < 12.5 < 12.5
Trichophyton rubrum 296 31.25 62.5 < 12.5 < 12.5
Trichophyton rubrum 57 62.5 250 25 < 12.5
Epidermophyton floccosum 125 125 12.5 < 12.5
Scopulariopsis sp. 250 > 250 < 12.5 < 12.5
Aspergillus niger 250 125 100 < 12.5
Curvularia lunata 125 250 < 12.5 < 12.5
Magnaporthe grisea 250 250 nt nt
Botrytis cinerea > 250 > 250 nt nt
Candida albicans > 250 > 250 > 100 25
  1. nt-not Tested
  2. Fluconazole, Ketoconazole-standard antifungal agent
  3. Costunolide, Eremanthin-Isolated compound