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Table 1 Expression of selected genes exhibiting > 1.5-fold or < 0.67-fold changes in Drosophila S2 cells after exposure to 100 μM PA for 2h

From: Pharmacological modulation of histone demethylase activity by a small molecule isolated from subcritical water extracts of Sasa senanensis leaves prolongs the lifespan of Drosophila melanogaster

Accession number Gene symbol Gene description Fold change
Up-regulated genes    
NM_001103559 CG34330 _ 10.0
NM_001038793 CG _ 3.78
NM_057233 impL3 lactic DH 3.78
NM_141268 Hph fatiga 2.99
NM_001103964 CG9815 _ 2.93
NM_140239 CG11652 _ 2.82
NM_080713 fok fledgling of Klp38B 2.80
NM_057947 Thor eukaryotic initiation factor 4E-binding protein 2.26
NM_001144611 bnl fibroblast growth factor 2.24
NM_058032 Fpps Famesyl diphosphate synthase 2.15
Nm_079270 Hsp67Bc Gene 3 2.07
NM_137458 Dgp-1 Dgp-1 2.02
NM_080173 GstD2 Glutathione S transferase D2 1.81
NM_170034 Gclm Glutathione-cysteine ligase modifier submit 1.81
NM_138269 cue cueball 1.68
NM_135115 CG14005 _ 1.67
NM_001032272 CG3785///CG33786 _///_ 1.65
NM_001170286 _ _ 1.64
NM_001031943 Hsp22///Hsp67Bb heat shock protein hsp22///Gene 2 1.63
NM_143700 CG17724///seq _///sequoia 1.63
NM_141334 CG10979 _ 1.61
NM_134584 CG32512 _ 1.61
NM_001043271 SNF4Agamma Lochrig 1.61
NM_140199 scyl scylla 1.59
NM_144004 CG3348 _ 1.58
NM_206410 asaragine-synthetase asparagine synthetase 1.57
NM_135328 Spn28D Dm-serpin-28D 1.57
NM_001144540 CG2017 GP-1 related 1.55
NM_137485 GstE7 Glutathione S transferase E7 1.52
Down-regulated genes    
NM_138240 CG9194 _ 0.55
NM_143815 Invadolysin invadolysin 0.59
NM_140792 MYPT-75D MYPT-75D 0.59
NM_136764 wde Windei 0.60
NM_057696 Ret Ret oncogene 0.60
NM_079534 alpha-Est 9 fragment J 0.62
NM_130578 CG32809 _ 0.62
NM_079937 sls sallimus 0.62
NM_001014750 mnb minibrain 0.62
NM_079578 jumu Domina 0.63
NM_080370 ltd lightoid 0.63
NM_001103650 Btk29A Btk family kinase at 29A 0.63
NM_168566 CG32135 _ 0.63
NM_206332 Muc68Ca Muc in 68Ca 0.64
NM_001031884 CG33691///CG33692 /// 0.64
NM_176545 unk unkempt 0.65
NM_168366 CG42268 CG32044 0.65
NM_001169959 Sema-5c Semaphorin 5C 0.65
NM_078959 Prx2540-2 peroxiredoxin 2540 0.66
NM_001104450 jigr1 CG17383 0.66
NM_001169949 Pi3K68D dPI 3-kinase 0.66
NM_001169228 fs(1)h rancor 0.66
NM_078607 dah Apodystrophin 0.67
NM_137485 GstE7 Glutathione S transferase E7 1.52
  1. Fold changes relative to vehicle-treated cells. Genes were differentially transcribed at p<0.05 (t-test).