Table 6 Effect of the methanolic extract of Phyllanthus muellerianus on different sera biochemical parameters of male and female rats
Dose (g/kg) | Sex | ALAT (UI) | ASAT (UI) | Creatinine (mg/l) | Urea (mg/l) |
|---|---|---|---|---|---|
0 | Male | 44.60 ± 11.64 | 41.83 ± 0.18 | 9.00 ± 1.58 | 157.21 ± 1.47 |
|  | Female | 43.50 ± 10.00 | 42.00 ± 4.21 | 9.25 ± 2.04 | 155.81 ± 1.33 |
4 | Male | 41.66 ± 2.92 | 38.66 ± 2.37 | 7.50 ± 5.27 | 155.10 ± 1.18 |
|  | Female | 42.50 ± 2.15 | 40.28 ± 1.95 | 7.27 ± 4.52 | 148.21 ± 1.22 |
8 | Male | 75.66 ± 5.48* | 63.00 ± 1.82* | 9.25 ± 2.44 | 159.40 ± 1.31 |
|  | Female | 76.20 ± 4.21* | 63.12 ± 1.51* | 9.70 ± 2.21 | 169.18 ± 1.41 |
12 | Male | 86.00 ± 1.73* | 160.50 ± 1.82** | 9.10 ± 4.33 | 161.21 ± 1.60 |
|  | Female | 76.90 ± 3.10* | 160.01 ± 2.31** | 9.55 ± 3.12 | 158.21 ± 1.25 |
16 | Male | 125.33 ± 6.21** | 145.33 ± 12.14** | 15.25 ± 2.85* | 184.2 ± 1.58* |
|  | Female | 116.01 ± 3.57** | 149.98 ± 8.24** | 13.29 ± 5.41* | 186.8 ± 0.92* |
20 | Male | 124.33 ± 6.21** | 144.33 ± 12.14** | 25.25 ± 2.85** | 219.24 ± 2.28** |
|  | Female | 123.01 ± 3.57** | 123.78 ± 8.24** | 21.29 ± 5.41** | 215.58 ± 2.36** |