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Table 3 Phytochemical analysis of total alkaloid content, total phenolic content and radical-scavenging activity of leaf extracts of Apocynaceae species

From: Assessment of antiproliferative and antiplasmodial activities of five selected Apocynaceae species

Species

MeOH crude extract

aSequential extract

  

HEX

DCM

DCM:MeOH

MeOH

b Total alkaloid content (mg BE/g)

    

Kopsia fruticosa

100 ± 4.2

63 ± 1.1

129 ± 4.0

99 ± 2.5

46 ± 1.6

Dyera costulata

58 ± 2.5

2.4 ± 0.6

11 ± 1.8

68 ± 2.7

41 ± 2.4

Alstonia angustiloba

23 ± 0.3

13 ± 2.3

27 ± 3.1

58 ± 1.2

27 ± 1.0

Calotropis gigantea

2.7 ± 0.3

3.7 ± 1.0

8.6 ± 1.2

9.6 ± 1.9

9.2 ± 2.7

Vallaris glabra

2.7 ± 0.4

4.4 ± 0.8

8.9 ± 0.6

9.2 ± 0.2

8.7 ± 2.2

b Total phenolic content (mg GAE/g)

    

Dyera costulata

319 ± 5.5

21 ± 0.2

23 ± 0.1

354 ± 6.0

279 ± 3.0

Vallaris glabra

99 ± 3.8

15 ± 0.9

24 ± 0.5

134 ± 1.0

164 ± 13

Kopsia fruticosa

83 ± 1.1

39 ± 0.5

20 ± 0.5

129 ± 1.0

84 ± 1.0

Alstonia angustiloba

68 ± 2.0

17 ± 0.6

24 ± 0.6

96 ± 1.1

94 ± 1.1

Calotropis gigantea

28 ± 0.8

14 ± 0.6

44 ± 1.7

42 ± 0.8

33 ± 0.5

b Radical-scavenging activity (mg AA/g)

    

Dyera costulata

377 ± 25

15 ± 0.3

9.3 ± 0.5

349 ± 21

278 ± 5.4

Vallaris glabra

84 ± 0.5

6.0 ± 0.3

8.4 ± 0.4

77 ± 2.2

119 ± 6.8

Kopsia fruticosa

63 ± 3.2

12 ± 1.4

7.5 ± 0.3

70 ± 2.0

48 ± 1.5

Alstonia angustiloba

29 ± 0.9

10 ± 0.2

5.7 ± 0.7

50 ± 1.2

46 ± 2.2

Calotropis gigantea

7.6 ± 0.4

5.6 ± 0.3

6.1 ± 0.4

8.0 ± 0.6

14 ± 1.3

  1. a HEX, hexane; DCM, dichloromethane; MeOH, methanol.
  2. b BE, boldine equivalent; GAE, gallic acid equivalent; AA, ascorbic acid. Values are in milligram per gram of extract.