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Table 2 Antibiofilm effect of thymoquinone against four positive biofilm strains

From: Antibacterial activity of Thymoquinone, an active principle of Nigella sativa and its potency to prevent bacterial biofilm formation

Strains

Inhibition of biofilm development (%)

 

Crystal Violet assay

XTT assay

 

aBIC50 (µg/ml)

bBIC90 (µg/ml)

BIC50 (µg/ml)

BIC90 (µg/ml)

Enterococcus faecalis ATCC 29212

85

349

44

145

Staphylococcus aureus ATCC 25923

22

75

20.5

51

Staphylococcus epidermidis CIP 106510

60

109

40

90

Pseudomonas aeruginosa ATCC 27853

>512

>512

>512

>512

  1. a, minimum biofilm inhibition concentration of TQ that showed 50% inhibition on the biofilm formation.
  2. b, minimum biofilm inhibition concentration of TQ that showed 90% inhibition on the biofilm formation.