Figure 8

Effect of Acorus calamus on chronic constriction injury induced histopathological changes. Figures 8a-8f show transverse-section of sciatic nerve of sham, CCI, vehicle, AC (100 and 200 mg/kg) and pregabalin pretreated groups respectively. In figure 8a and 8f, blue arrow shows normal fiber arrangement. In figures 8b-8e, black arrows show fiber derangement (thin arrow), swelling (bold arrow) of nerve fiber and presence of activated satellite cells and Schwann cells (arrow head). In figures 8d-8f, show attenuation of CCI induced swelling of nerve fibers by AC (100 and 200 mg/kg) and pregabalin pretreatment groups respectively. Microscopic examinations were performed under 450 × light microcopy, scale bar 35 μm.