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Table 3 Extent of exposure (maximum 24 ampoules = 100%), percentage of subjects with local reactions and tolerability.

From: Safety and effects of two mistletoe preparations on production of Interleukin-6 and other immune parameters - a placebo controlled clinical trial in healthy subjects

 

Iscucin®Populi

Viscum Mali e planta tota

Placebo

 

(n = 30)

(n = 21)

(n = 20)

 

0.0125%

0.25%

5%

1:1000

1:100

1:50

   
 

strength

strength

strength

D3

D2

2%

   
 

F

G

H

      
 

Week

Week

Week

Week

Week

Week

Week

Week

Week

 

1-4

5-8

9-12

1-4

5-8

9-12

1-4

5-8

9-12

Overall injected ampoules (%)

100.0

81.7

64.0

100.0

100.0

99.1

99.7

99.8

99.9

Local reactions %

17

93

93

0

19

19

0

0

0

Tolerability (%)

 

**

**

  

*

   

Bad

0

28

21

0

0

0

0

0

0

Moderate

3

38

45

0

0

0

5

0

0

Good

21

34

34

5

14

29

0

0

0

Excellent

76

0

0

95

86

71

95

100

100

  1. *p < 0.05 versus Placebo, **p < 0.001 versus Placebo. Significant deviations are bold typed.