Table 7 Effects of SAME on renal TBARS, GSH and DNA fragmentation of rat
From: Prevention of hepatorenal toxicity with Sonchus asper in gentamicin treated rats
Treatment | TBARS (nM /mg protein) | GSH (μM/g tissue) | DNA fragmentation% |
|---|---|---|---|
Control (Saline, 0.9% NaCl) | 58.77 ± 6.4AB | 0.82 ± 0.02A | 0.21 ± 0.09A |
GTM (100 mg/kg bw) | 81.07 ± 7.92D | 0.56 ± 0.03D | 2.14 ± 0.11C |
GTM + SAME (100 mg/kg bw) | 70.48 ± 6.78C | 0.67 ± 0.03C | 1.62 ± 0.28C |
GTM + SAME (200 mg/kg bw) | 61.10 ± 5.82B | 0.76 ± 0.04B | 0.95 ± 0.14B |
SAME (200 mg/kg bw) | 59.62 ± 7.03AB | 0.84 ± 0.03A | 0.22 ± 0.04A |