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Table 7 Effects of SAME on renal TBARS, GSH and DNA fragmentation of rat

From: Prevention of hepatorenal toxicity with Sonchus asper in gentamicin treated rats

Treatment TBARS (nM /mg protein) GSH (μM/g tissue) DNA fragmentation%
Control (Saline, 0.9% NaCl) 58.77 ± 6.4AB 0.82 ± 0.02A 0.21 ± 0.09A
GTM (100 mg/kg bw) 81.07 ± 7.92D 0.56 ± 0.03D 2.14 ± 0.11C
GTM + SAME (100 mg/kg bw) 70.48 ± 6.78C 0.67 ± 0.03C 1.62 ± 0.28C
GTM + SAME (200 mg/kg bw) 61.10 ± 5.82B 0.76 ± 0.04B 0.95 ± 0.14B
SAME (200 mg/kg bw) 59.62 ± 7.03AB 0.84 ± 0.03A 0.22 ± 0.04A
  1. Mean ± SD (n = 06). A-D, Means not sharing common letters within a column are significantly (P < 0.01) different from each other.
  2. GTM, gentamicin; SAME, methanol extract of Sonchus asper