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Table 2 EGFR signals and apoptosis mediators

From: American ginseng suppresses Western diet-promoted tumorigenesis in model of inflammation-associated colon cancer: role of EGFR

Protein AOM/DSS +ginseng
pEGFR 2.2 ± 0.3* 1.1 ± 0.2†
pErbB2 2.8 ± 0.4* 1.6 ± 0.1†
pERK 8.3 ± 0.1* 5.8 ± 0.3*,†
pAKT 7.2 ± 0.3* 4.4 ± 0.8*,†
Cox-2 3.1 ± 0.3* 1.9 ± 0.2*,†
PCNA 10.7 ± 1.2* 6.3 ± 0.1*,†
Bax 1.6 ± 0.3 2.0 ± 0.1*,†
Bcl2 1.1 ± 0.1 1.1 ± 0.2
c-Jun 1.2 ± 0.2 0.6 ± 0.2†
p27Kip1 1.0 ± 0.5 0.9 ± 0.1
p21Waf1 1.8 ± 0.2 3.8 ± 0.1*,†
CCND1 2.9 ± 0.6* 2.7 ± 0.4*
  1. *p < 0.05, compared to vehicle treated on WD; †p < 0.05 compared to AOM/DSS on WD; n = 4 tumors in each group.