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Table 4 Minimal inhibitory concentration (MIC) of the studied spice extracts and CHL on the studied bacterial species.

From: Antibacterial activities of selected Cameroonian spices and their synergistic effects with antibiotics against multidrug-resistant phenotypes

 

Tested samples and MIC in μg/ml in the absence and presence of PAßN (in parenthesis)

Bacterial strains

F .

xanthoxyloides

D .

glomerata

A .

citratum

B. cinnamomea

E .

giganteus

M .

whitei

S .

melongena

O .

subscorpioidea

P .

capense

X .

aethiopica

S. zenkeri

CHL

E. coli

           

ATCC8739

- (1024)

1024 (512)

1024 (256)

- (256)

- (-)

- (1024)

- (128)

- (-)

- (512)

- (512)

- (-)

4 (< 2)

ATCC10536

1024

512 (128)

1024

1024

1024

1024

-

512

256

64

256

< 2 (< 2)

AG100

256

512 (256)

1024 (1024)

1024 (1024)

1024 (1024)

1024 (-)

1024 (-)

512 (-)

- (1024)

1024 (1024)

- (-)

8 (< 2)

AG100A

1024

1024 (256)

1024

1024

1024

-

-

1024

1024

-

-

< 2 (< 2)

AG100ATET

-

1024 (512)

1024

512

1024

-

-

-

1024

1024

-

64 (< 2)

AG102

1024

512 (256)

1024

512

1024

-

-

1024

1024

1024

-

32 (< 2)

MC4100

256

256(< 8)

512

256

512

1024

1024

1024

1024

1024

-

32

W3110

- (512)

256 (< 8)

512 (< 8)

1024 (< 8)

1024 (1024)

1024 (512)

-

512 (512)

1024 (1024)

- (-)

- (-)

4 (< 2)

E. aerogenes

-

           

ATCC13048

-

512 (512)

1024

512

-

-

-

-

-

-

-

8 (< 2)

CM64

- (-)

512 (512)

- (1024)

1024 (1024)

1024 (1024)

1024 (-)

- (-)

- (-)

- (-)

- (-)

- (-)

256 (8)

EA3

1024

1024 (1024)

-

1024

-

-

-

1024

1024

-

-

- (128)

EA27

1024

512 (256)

1024

1024

1024

1024

-

512

1024

1024

-

256 (< 2)

EA289

-

1024 (1024)

1024

512

1024

-

-

-

-

-

-

- (64)

EA298

-

1024 (128)

-

1024

-

1024

-

256

512

1024

128

64 (< 2)

EA294

256

128

512

64

256

-

1024

256

256

256

512

8

E. cloacae

           

ECCI69

512 (-)

1024 (1024)

1024 (1024)

1024 (512)

1024 (-)

- (-)

- (-)

- (-)

-

-(1024)

- (256)

- (16)

BM47

1024 (1024)

1024 (256)

1024 (1024)

1024 (1024)

1024 (-)

- (-)

- (-)

- (-)

512(64)

1024(1024)

- (-)

- (< 2)

BM67

1024 (1024)

1024 (128)

1024

1024

-

-

-

-

512

1024

-

256 (16)

K. pneumoniae

           

ATCC11296

1024 (1024)

512 (128)

512 (512)

256 (256)

1024 (256)

- (1024)

- (1024)

1024 (512)

1024 (256)

- (-)

- (-)

4 (< 2)

KP55

1024

512 (256)

1024

512

-

-

-

1024

1024

-

-

64 (2)

KP63

1024

512 (< 8)

256

512

512

1024

512

256

256

64

-

64 (< 2)

K24

512

512 (32)

512

256

32

1024

1024

-

1024

-

-

16 (< 2)

K2

-

1024 (128)

-

1024

-

-

-

1024

512

-

-

32 (4)

P. stuartuii

           

NEA16

1024

512 (32)

128

256

1024

1024

1024

512

256

512

1024

32 (8)

ATCC29914

1024

1024 (512)

512

512

1024

1024

-

-

1024

-

-

16 (8)

PS2636

-

512

1024

1024

-

-

-

-

-

-

-

32

PS299645

1024 (-)

256 (256)

256

256 (512)

- (-)

- (-)

- (512)

- (-)

- (-)

- (-)

- (-)

32 (< 2)

P. aeruginosa

           

PA01

-

1024 (512)

1024

1024

-

-

-

-

-

1024

-

16 (< 2)

PA124

-

512 (512)

-

1024

-

1024

-

-

-

-

-

32 (< 2)

  1. (-): MIC not detected at up to 1024 μg/ml for the les extracts and 256 μg/ml for CHL. (): values in parenthesis are MIC of substance in the presence of PAßN at 30 μg/ml. The MIC of PAßN was 64 μg/ml on E. coli, AG100A, 512 μg/ml on ATCC11296, BM67, EA27, EA289; 1024 μg/ml on AG100ATET, ATCC13048, CM64; and > 1024 μg/ml on other bacteria. CHL: chloramphénicol