Echinacea-induced cytosolic Ca2+ elevation in HEK293

Table 1 GC-MS analysis of identified compounds in the 6 bioactive fractions of E. purpurea root extract ^a.

	Fraction 68		Fraction 72		Fraction 75		Fraction 80		Fraction 83		Fraction 94
Compound	% by Dry Weight	μM	% by Dry Weight	μM	% by Dry Weight	μM	% by Dry Weight	μM	% by Dry Weight	μM	% by Dry Weight	μM
Bauer alkamide 1+2	2.8	0.41	Nd	Nd	Nd	Nd	Nd	Nd	Nd	Nd	Nd	Nd
Chen alkamide	11.5	1.56	2.8	2.38	Nd	Nd	Nd	Nd	Nd	Nd	Nd	Nd
Bauer alkamide 10	Nd	Nd	1.2	1	15.1	0.19	0.4	0.01	Nd	Nd	0.8	1.33
Bauer alkamide 11	Nd	Nd	Nd	Nd	Nd	Nd	6.7	0.13	11.2	0.74	6.5	10.7
Bauer alkamide 8+9	Nd	Nd	41.9	35.32	46.9	0.61	2.5	0.05	4.6	0.31	1.8	3.01
Bauer alkamide 4	11.5	1.56	Nd	Nd	Nd	Nd	Nd	Nd	Nd	Nd	Nd	Nd
Bauer alkamide 6	5.1	0.66	Nd	Nd	Nd	Nd	Nd	Nd	Nd	Nd	Nd	Nd

^a The chemical identification of these alkamides in this E. purpurea accession, and the systematic chemical nomenclature for these alkamides have been previously described [3]. All identified constituents were confirmed via GC-MS with synthetic standards. Nd: not detectable.

ISSN: 2662-7671