Figure 7From: Curcumin activates the p38MPAK-HSP25 pathway in vitro but fails to attenuate diabetic nephropathy in DBA2J mice despite urinary clearance documented by HPLC Curcumin did not lower U 12-HETE/cr excretion in noDM and DM mice. Urinary 12-HETE/cr ratios for noDM and DM mice fed chow with 0 and 5,000 ppm curcumin. Mice were fed curcumin post-Stz injections (Experiment 1). Graph represents pooled data (day 9 and 15). *P < 0.05; #P < 0.01.Back to article page