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Table 2 Effect of extracts on the viability of microfilariae at 120 hours in secondary screens

From: Selective activity of extracts of Margaritaria discoidea and Homalium africanum on Onchocerca ochengi

Concentration of extract (μg/mL)

% Inhibition of microfilarial motility

 

MRH

MLC

HLH

HLC

Negative control*

500

100

100

100

100

0

250

100

100

100

100

0

125

100

100

100

100

0

62.5

100

50

0

100

0

31.25

0

0

0

50

0

15.63

0

0

0

0

0

7.81

0

0

0

0

0

3.91

0

0

0

0

0

0

0

0

0

0

0

  1. All four extracts codes are defined in Table 1. *The negative control wells contained worms in culture medium with 2% DMSO only.