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Table 3 Cytotoxicity of 5-FU and ethanolic extracts from 5 medicinal plants and one recipe with promising activity

From: Cytotoxic activity of Thai medicinal plants against human cholangiocarcinoma, laryngeal and hepatocarcinoma cells in vitro

Plants

Cell line

 

CL-6

HepG2

Hep-2

HRE

 

IC50

SI

IC50

SI

IC50

SI

IC50

Atractylodes lancea

24.09 ± 3.40

8.6

76.68 ± 15.94

2.7

29.35 ± 8.66

7.1

207.59 ± 7.97

Kaempferia galangal (leaf)

37.36 ± 3.98

2.9

115.47 ± 26.23

0.9

18.99 ± 10.33

5.7

119.20 ± 14.91

Zingiber officinal

34.26 ± 7.65

3.5

9.67 ± 3.91

12.6

32.40 ± 6.70

3.8

121.50 ± 5.20

Piper chaba

40.74 ± 5.30

4.5

68.09 ± 22.58

2.7

18.93 ± 5.03

9.8

119.14 ± 9.94

Pra-Sa-Prao-Yhai recipe

44.12 ± 11.58

5.9

125.07 ± 3.08

2.11

20.99 ± 2.68

12.5

263.51 ± 29.06

Mesua ferrea

48.23 ± 5.84

2.5

86.47 ± 4.38

1.4

19.22 ± 5.31

6.3

121.77 ± 29.08

5-FU (μM)

757.00 ± 77.16

2.0

633.08 ± 284.25

2.4

141.49 ± 17.14

10.8

1542.20 ± 1529.11

  1. Data are presented otherwise specified as mean ± SD of IC50 (μg/ml) from 3 independent experiments, triplicate for each.