Parameter | Group | N | Min | Max | Mean ± S.D. | Percent Change | P valuea | P valueb |
---|---|---|---|---|---|---|---|---|
LPO (U\ml) | Control | 10 | 2.70 | 5.00 | 3.68 ± 0.84 | 100.00 | 0.001 | |
VPA | 10 | 3.10 | 3.90 | 3.52 ± 0.24 | 95.65 | 0.573 | ||
VPA-CUR | 10 | 1.40 | 3.40 | 2.46 ± 0.55c | 66.73 | 0.001 | ||
CUR | 10 | 1.40 | 3.70 | 2.56 ± 0.82c | 69.57 | 0.007 | ||
GSSG (pg/ml) | Control | 10 | 65.00 | 125.00 | 92.50 ± 23.24 | 100.00 | 0.001 | |
VPA | 10 | 150.00 | 310.00 | 225.00 ± 51.91c | 243.24 | 0.001 | ||
VPA-CUR | 10 | 225.00 | 460.00 | 345.00 ± 81.99c | 372.97 | 0.001 | ||
CUR | 10 | 100.00 | 180.00 | 138.50 ± 21.48 | 149.73 | 0.001 | ||
GSH (pg\ml) | Control | 10 | 7104.06 | 9134.06 | 8016.97 ± 638.64 | 100.00 | 0.001 | |
VPA | 10 | 3506.25 | 5417.81 | 4397.66 ± 557.53c | 54.85 | 0.001 | ||
VPA-CUR | 10 | 4419.06 | 6040.94 | 5099.31 ± 485.93c | 63.61 | 0.001 | ||
CUR | 10 | 6825.00 | 9638.75 | 8190.53 ± 948.88 | 102.16 | 0.637 | ||
GSTs (mU\ml) | Control | 10 | 8.50 | 20.50 | 15.35 ± 3.98 | 100.00 | 0.001 | |
VPA | 10 | 11.60 | 18.40 | 13.84 ± 2.00 | 90.19 | 0.304 | ||
VPA-CUR | 10 | 8.50 | 17.00 | 12.74 ± 2.74 | 83.00 | 0.105 | ||
CUR | 10 | 5.50 | 17.00 | 11.57 ± 3.78c | 75.37 | 0.043 | ||
GSH/GSSG | Control | 10 | 59.15 | 140.52 | 92.59 ± 27.69 | 100.00 | 0.001 | |
VPA | 10 | 13.87 | 31.68 | 20.54 ± 5.53c | 22.19 | 0.001 | ||
VPA-CUR | 10 | 9.61 | 22.22 | 15.64 ± 4.24c | 16.89 | 0.001 | ||
CUR | 10 | 47.43 | 87.58 | 60.33 ± 11.63c | 65.16 | 0.005 |