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Table 1 Active compounds of Chuanxiong Rhizoma, the dried rhizome of Ligusticum Chuanxiong

From: Neuroprotective effects of methanolic extract from Chuanxiong Rhizoma in mice with middle cerebral artery occlusion-induced ischemic stroke: suppression of astrocyte- and microglia-related inflammatory response

Mol ID

Molecule name

MW

OB (%)

Caco-2

DL

Structure

MOL001494

Mandenol

308.56

42

1.46

0.19

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MOL002135

Myricanone

356.45

40.6

0.67

0.51

MOL002140

Perlolyrine

264.3

65.95

0.88

0.27

MOL002151

Senkyunone

326.52

47.66

1.15

0.24

MOL002157

Wallichilide

412.57

42.31

0.82

0.71

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MOL000359

Sitosterol

414.79

36.91

1.32

0.75

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  1. Abbreviations: Mol Molecule, MW Molecular weight, OB Oral bioavailability, Caco-2 Caco-2 cells permeability, DL Drug-likeness
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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