Study outcomes | Curamin | Placebo | Curamed | Intergroup comparison, mean difference or difference in rank sum$ and p values | |
---|---|---|---|---|---|
Placebo vs Curamin | Placebo vs Curamed | ||||
WOMAC osteoarthritis total Index | 7.38 ± 10.02* | 2.26 ± 10.39 | 6.34 ± 11.38 | −5.12 | −4.08 |
−24.84 $ | −17.18 $ | ||||
ES | 0.50 | 0.37 | P < 0.05* | P > 0.05 | |
WOMAC joint pain index | 2.02 ± 2.93* | 0.69 ± 2.70 | 1.86 ± 2.95 | −1.32 | −1.167 |
P < 0.05* | P > 0.05 | ||||
ES | 0.47 | 0.41 | |||
WOMAC morning stiffness index | 0.46 ± 1.35 | 0.14 ± 1.58 | 0.40 ± 1.54 | −12.43 $ | −9.12 $ |
P > 0.05 | P > 0.05 | ||||
ES | 0.22 | 0.17 | |||
WOMAC limitation of physical function index | 4.61 ± 6.66 | 1.34 ± 7.01 | 3.83 ± 7.56 | −3.27 | −2.49 |
P > 0.05 | P > 0.05 | ||||
ES | 0.48 | 0.34 | |||
Chair Stand Test Score | 1.74 ± 2.18* | 0.44 ± 2.91 | 1.87 ± 2.41** | 1.30 | 1.44 |
P < 0.05* | P < 0.01** | ||||
ES | 0.51 | 0.53 | |||
Fast Paced Walk Test Speed, m/s. | 0.10 ± 0.18** | 0.01 ± 0.22 | 0.08 ± 0.05* | 0.12 | 0.10 |
P < 0.01** | P < 0.05* | ||||
ES | 0.45 | 0.44 | |||
Time up and go test, sec. | 1.56 ± 2.04** | 0.17 ± 0.84 | 0.78 ± 1.98 | −1.39 | −0.59 |
P < 0.01** | P > 0.05 | ||||
ES | 0.89 | 0.40 | |||
Stair Climb Test, sec. | 2.03 ± 3.60** | 0.22 ± 2.84 | 1.66 ± 2.37 | −1.82 | −0.95 |
P < 0.01** | P > 0.05 | ||||
ES | 0.56 | 0.55 | |||
Blood test 1: ESR | −2.75 ± 0.77 | −4.98 ± 0.85 | −4.12 ± 0.88 | 16.63$ p > 0.05 | −7.09$ p > 0.05 |
Blood test 2: CRP | −0.787 ± 0.33 | −1.376 ± 0.31 | −1.274 ± 0.35 | 18.28$ p > 0.05 | −8.67$ p > 0.05 |