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An ethyl acetate fraction derived from Houttuynia cordata extract inhibits the production of inflammatory markers by suppressing NF-кB and MAPK activation in lipopolysaccharide-stimulated RAW 264.7 macrophages

  • Jin Mi Chun1,
  • Kyoung Jin Nho1,
  • Hyo Seon Kim1,
  • A Yeong Lee1,
  • Byeong Cheol Moon1 and
  • Ho Kyoung Kim1Email author
BMC Complementary and Alternative MedicineThe official journal of the International Society for Complementary Medicine Research (ISCMR)201414:234

DOI: 10.1186/1472-6882-14-234

Received: 16 August 2013

Accepted: 30 June 2014

Published: 10 July 2014

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
16 Aug 2013 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
18 Nov 2013 Reviewed Reviewer Report - Man Hee Rhee
12 May 2014 Reviewed Reviewer Report - Lang He
13 May 2014 Reviewed Reviewer Report - Shih-Chang Chien
13 Jun 2014 Author responded Author comments - Jin Mi Chun
Resubmission - Version 3
13 Jun 2014 Submitted Manuscript version 3
30 Jun 2014 Editorially accepted
10 Jul 2014 Article published 10.1186/1472-6882-14-234

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

Herbal Medicine Resources Group, Korea Institute of Oriental Medicine