There are 6000 species of plants occurring in Pakistan that indicate its potential wealth. 700 species of these are used for their medicinal values, while several of them are exported . Several hundred species are used in herbal remedies, in indigenous system of medicine, because of their medicinal importance that may be attributed to their phytochemicals .
R. fruticosus is locally known as “Karwara” . It grows mostly in Northern areas of Pakistan like Malakand, Kotli, Chitral and Dir districts of Khyber Pakhtunkhwa. The plant is scrambling perennial shrub, which belongs to family Rosaceae. The family is largest dicot family of vascular plants which comprises 85 genera and 3000 species, all of which are mostly located in tropics to alpine pastures of Pakistan as evergreen or deciduous trees, shrubs and herbs .
R. fruticosus is a perennial shrub, with spiny branches, leaves tri or penta foliate; leaflets leathery, elliptic or obviate, toothed, green above, grey-woolly beneath, the terminal largest; leaf stalk with long bristles; flowers white, in dense short branched cluster and fruits are black.
It contains ascorbic acid, organic acids, tannins and volatile oils . On the basis of these chemical constituents, the plant is very useful antidiarrheal and soothes inflamed mucosa. Decoction of leaves is used as tonic and gargle. Poultice of the leaves is applied to abscesses and skin ulcers [6, 7].
Its ethno-medical and biological activities include anti-inflammatory, antimicrobial and antioxidant. The plant is traditionally used in the treatment of wound healing, dysentery, diarrhoea, haemorrhoids, cystitis and diabetes mellitus . Since the plant has potential medicinal properties as antispasmodic and anthelmintic, therefore, we conducted current work to investigate: 1) the antispasmodic activity of R. fruticosus in the context of abdominal pain, and 2) the anthelmintic activity of R. fruticosus.